Dr. Shimizu’s paper has been published in Bioengineering 

October 8, 2026

A paper by Dr. Tomohiro Shimizu of Hokkaido University’s Faculty of Medicine has been published in Bioengineering .

  • Ohashi, Yusuke, Tomohiro Shimizu, Hidenori Koyano, Yumejiro Nakamura, Daisuke Takahashi, Katsuhisa Yamada, and Norimasa Iwasaki. 2025. Evaluation of Operator Variability and Validation of an AI-Assisted α-Angle Measurement System for DDH Using a Phantom Model. Bioengineering 12, no. 9: 1004
    DOI: https://doi.org/10.3390/bioengineering12091004

Abstract

Ultrasound examination using the Graf method is widely applied for early detection of developmental dysplasia of the hip (DDH), but intra- and inter-operator variability remains a limitation. This study aimed to quantify operator variability in hip ultrasound assessments and to validate an AI-assisted system for automated α-angle measurement to improve reproducibility. Thirty participants of different experience levels, including trained clinicians, residents, and medical students, each performed six ultrasound scans on a standardized infant hip phantom. Examination time, iliac margin inclination, and α-angle measurements were analyzed to assess intra- and inter-operator variability. In parallel, an AI-based system was developed to automatically detect anatomical landmarks and calculate α-angles from static images and dynamic video sequences. Validation was conducted using the phantom model with a known α-angle of 70°. Clinicians achieved shorter examination times and higher reproducibility than residents and students, with manual measurements systematically underestimating the reference α-angle. Static AI produced closer estimates with greater variability, whereas dynamic AI achieved the highest accuracy (mean 69.2°) and consistency with narrower limits of agreement than manual measurements. These findings confirm substantial operator variability and demonstrate that AI-assisted dynamic ultrasound analysis can improve reproducibility and reliability in routine DDH screening.

Keywords: Developmental Dysplasia of the Hip (DDH); ultrasound imaging; Artificial Intelligence (AI); α-angle measurement; operator variability

Credit: © 2025 by the authors. Originally published in Bioengineering, 12(9), 1004. https://doi.org/10.3390/bioengineering12091004. Licensed under CC BY 4.0.